Sit on the Left side of the plane for the best views on flights from Boston to Denver. Left side wins both departure and arrival. At departure you get Boston Harbor and the skyline, and at arrival you get the best angle on the Front Range and Denver. Over the Great Plains the views are similar on both sides, but the left side has a slight edge catching the Missouri River crossings and the early Rocky Mountain foothills as you approach Colorado.

During takeoff from General Edward Lawrence Logan International (BOS), sit on the Left side for the best views. Logan's most common westbound departures use runway 22L/22R heading southwest, or runway 33L heading northwest. On a westbound departure, the left side gets Boston Harbor, the downtown skyline, and the Charles River basin as the aircraft turns west. The right side faces inland toward suburban sprawl with little of interest. Notable sights include: Boston Harbor and its islands, downtown Boston skyline (Prudential Tower, Hancock Tower), Charles River and Cambridge, Fenway Park area.

When landing at Denver International (DEN), sit on the Left side for the best views. Denver International sits east of the city, and aircraft typically approach from the east on runway 16L/16R heading south, or from the west on runway 34 heading north. On the common east approach heading south, the left side faces east toward the plains — less interesting. However on the more scenic west approach heading north or northwest, the left side gets the Front Range and Rocky Mountains. On balance, left side more reliably captures the Denver skyline and the dramatic Front Range as the aircraft descends over the metro area regardless of runway direction. Notable sights include: Rocky Mountain Front Range (including Longs Peak and Mount Evans), Denver downtown skyline, Cherry Creek Reservoir, the distinctive white tensile roof of DEN terminal.

The flight from General Edward Lawrence Logan International (BOS) to Denver International (DEN) takes Approximately 4 hours 15 minutes.

The flight tracks roughly along 41-42 degrees north latitude, crossing upstate New York and the Finger Lakes region, then over the flat agricultural grid of northern Ohio and Indiana, across the Mississippi River near the Quad Cities area, over the Iowa and Nebraska plains, the Missouri River valley, and finally the High Plains of eastern Colorado before the dramatic rise of the Front Range becomes visible on the western horizon roughly 100 miles out from Denver.