Sit on the Left side of the plane for the best views on flights from Boston to Indianapolis. The left side delivers the more dramatic and memorable views: the Boston Harbor and skyline departure is genuinely spectacular, and through the cruise phase the left side tracks slightly north of the route centerline, offering better angles on the Berkshires, upstate New York terrain, and the Ohio River valley. The Indianapolis arrival view on the right is good but the flat Indiana landscape is less visually compelling overall.

During takeoff from General Edward Lawrence Logan International (BOS), sit on the Left side for the best views. Logan typically departs westbound on runway 22L/22R or 27, meaning a left-side seat faces south toward Boston Harbor, the downtown skyline, and the harbor islands. You get a clear view of the city grid and waterfront as the aircraft banks west toward the route. Notable sights include: Boston Harbor and harbor islands, downtown Boston skyline (Financial District and Back Bay), Charles River and Cambridge, Massachusetts Bay coastline.

When landing at Indianapolis International (IND), sit on the Right side for the best views. Indianapolis International typically uses runway 23L/23R for arrivals from the east, with the approach heading southwest. A right-side seat faces northwest, giving a view over the Indianapolis downtown skyline and the urban grid as the aircraft descends on final approach. Notable sights include: Indianapolis downtown skyline and Monument Circle area, White River corridor, Eagle Creek Reservoir to the northwest, flat Indiana agricultural grid.

The flight from General Edward Lawrence Logan International (BOS) to Indianapolis International (IND) takes Approximately 2 hours 15 minutes.

The flight crosses the Berkshire Hills of western Massachusetts (visible as rolling forested ridges), the Hudson River valley in New York, the Catskill Mountains to the north, then flattens out over the Ohio plains. The route passes near Cleveland and crosses into Indiana over the flat glaciated till plain. The Wabash River valley is visible on descent into Indianapolis.