Sit on the Left side of the plane for the best views on flights from Charleston to Denver. Left side wins both ends of the flight. At takeoff you get Charleston Harbor and the historic peninsula, and on approach to Denver the left side faces the Rocky Mountain Front Range — the single most spectacular view of the entire route. During the cruise, the left side also tracks slightly more toward the southern Appalachians over Georgia and Tennessee before the Great Plains open up.

During takeoff from Charleston Afb International (CHS), sit on the Left side for the best views. CHS runways 15/33 are the primary runways. Departing northwest toward Denver on runway 33, the left side faces south and east, giving views over the Charleston peninsula, the confluence of the Ashley and Cooper Rivers, and Charleston Harbor. The historic downtown grid and Fort Sumter island are clearly visible on the left during the climbing turn. Notable sights include: Charleston Harbor, Fort Sumter, Ashley-Cooper River confluence, Charleston peninsula downtown grid.

When landing at Denver International (DEN), sit on the Left side for the best views. Denver International sits east of the city, and aircraft typically land from the east on runway 16L/16R heading south, or from the west on runway 34. On a westbound approach from the east, the left side faces east and south with views of the flat plains, but on the more common eastward approach or circling, the left side picks up downtown Denver and the Front Range. On the standard ILS approach to runway 34 heading north, the left side faces west directly toward the Rocky Mountain Front Range — the most dramatic view of the flight. Notable sights include: Rocky Mountain Front Range, Longs Peak, Mount Evans, downtown Denver skyline.

The flight from Charleston Afb International (CHS) to Denver International (DEN) takes Approximately 3 hours 45 minutes to 4 hours 15 minutes.

The flight crosses the southern Appalachians over western North Carolina and Tennessee, then the Tennessee River valley. Over Arkansas and Missouri the terrain flattens into the Mississippi Alluvial Plain. Crossing into Kansas and Colorado the route traverses the High Plains — featureless but for the vast rectangular agricultural grid. The Smoky Hills of Kansas and the Arkansas River valley are subtle but visible. The Front Range appears on the horizon roughly 100 miles out from Denver.