Sit on the Left side of the plane for the best views on flights from Prague to Istanbul. While the right side wins at takeoff for Prague city views, the left side delivers the more spectacular payoff: the entire Istanbul approach with the Bosphorus, the historic peninsula skyline, and the Sea of Marmara is one of the most dramatic urban arrivals in Europe. The left side also tracks the Danube basin and Balkan highlands during cruise.

During takeoff from Ruzyne (PRG), sit on the Right side for the best views. Prague Ruzyne typically departs eastward on runway 06, so the right (south) side gives you a view over central Prague — the historic city center, Vltava river bends, and Prague Castle on Hradcany hill are all visible during the climb-out. The left side faces north toward flat suburban sprawl. Notable sights include: Prague Castle and Hradcany, Vltava river meanders through the city, Old Town and Wenceslas Square district, Vysehrad fortress on the river bluff.

When landing at Ataturk (IST), sit on the Left side for the best views. Ataturk Airport's primary arrival runway 06 brings aircraft in from the west over the Sea of Marmara, so the left (north) side gives you the Istanbul skyline, the Bosphorus strait, and the historic peninsula with its unmistakable silhouette of domes and minarets. The right side faces south toward the open Marmara. Notable sights include: Istanbul historic peninsula with Hagia Sophia and Blue Mosque domes, Bosphorus strait connecting Marmara to Black Sea, Galata Tower and Beyoglu district, Golden Horn inlet.

The flight from Ruzyne (PRG) to Ataturk (IST) takes Approximately 2 hours 45 minutes to 3 hours.

The flight crosses the Bohemian-Moravian Highlands leaving Czech Republic, then tracks over the Danube plain of Slovakia and Hungary with the Danube visible as a wide silver ribbon near Budapest. Over Serbia the terrain rises into the Balkan mountain ranges. The flight then crosses Bulgaria and descends over Thrace toward the Turkish coast and Sea of Marmara.