Sit on the Left side of the plane for the best views on flights from Atlanta to Panama City. While the right side wins at takeoff with Atlanta's skyline, the left side dominates the majority of the flight southward over the Caribbean coast of Central America and delivers the spectacular Panama Canal and Pacific skyline approach. The left side also captures the Cuban coastline and Yucatan Peninsula during cruise if routing goes that way.

During takeoff from The William B Hartsfield Atlanta International (ATL), sit on the Right side for the best views. ATL primarily uses runways 8L/8R/9L/9R for eastward departures or 26L/26R/27L/27R for westward. Southbound departures to PTY typically involve a left turn after takeoff heading south, putting the right side over downtown Atlanta's skyline and then the southern suburbs. The right side also captures Stone Mountain to the east during the climb-out. Notable sights include: Downtown Atlanta skyline, Stone Mountain (granite dome ~16 miles east of ATL), Lake Lanier to the northeast, Chattahoochee River corridor.

When landing at Tocumen International (PTY), sit on the Left side for the best views. Tocumen sits east of Panama City, and aircraft typically approach from the north or northwest on runway 03L/03R or 21L/21R. On approach from the north, the left side faces west toward Panama City's skyline on the Pacific coast and the Panama Canal's Pacific entrance at Miraflores and Pedro Miguel locks. This is one of the most distinctive approach views in the Americas. Notable sights include: Panama City Casco Viejo and modern skyline, Panama Canal Pacific entrance and Miraflores Locks, Bridge of the Americas, Pacific Ocean and Gulf of Panama.

The flight from The William B Hartsfield Atlanta International (ATL) to Tocumen International (PTY) takes Approximately 4 hours 15 minutes to 4 hours 45 minutes.

The flight path typically crosses the Gulf of Mexico or Caribbean Sea, passes over or near Cuba or the Yucatan Peninsula of Mexico, then tracks along the Caribbean coast of Central America over Honduras, Nicaragua, and Costa Rica before crossing into Panama. The mountainous spine of Central America's cordillera is visible below during the Costa Rica and Panama segments, including volcanic peaks of the Cordillera de Talamanca.