Sit on the Right side of the plane for the best views on flights from Miami to Medellin. The right side delivers the spectacular Miami Beach and Biscayne Bay departure, then over Cuba offers coastal views of the Sierra Maestra mountains in the distance, and along the Colombian coast you may catch glimpses of the Caribbean shoreline. The landing view on the left is better, but the takeoff and mid-flight scenery give the right side a slight overall edge for the full journey.

During takeoff from Miami International (MIA), sit on the Right side for the best views. MIA typically departs eastward on runways 08L/08R, then turns south toward Cuba. The right side gives you Biscayne Bay, the Miami Beach barrier islands, and the Atlantic coastline as you climb out and bank south. The left side faces inland toward the Everglades, which is flat and featureless at this stage. Notable sights include: Biscayne Bay, Miami Beach and South Beach barrier island, Port of Miami on Dodge Island, the Florida Keys chain beginning to appear to the south.

When landing at Olaya Herrera (EOH), sit on the Left side for the best views. EOH sits in the Aburrá Valley, a narrow north-south valley in the Andes. Aircraft typically approach from the north on runway 01, meaning the left side faces west toward the steep Andean ridgelines and the city of Medellín spread across the valley floor below. The right side faces east into the hillsides and has a more obstructed, less panoramic view of the city. Notable sights include: Medellín city center and urban valley floor, the steep Cordillera Central ridgelines flanking the Aburrá Valley, the Rio Medellín running through the valley, densely packed comunas climbing the eastern and western hillsides.

The flight from Miami International (MIA) to Olaya Herrera (EOH) takes Approximately 3 hours 30 minutes to 4 hours.

The flight crosses the Florida Straits and Cuba, where the Sierra Maestra range is visible in eastern Cuba. Over the Caribbean Sea, the San Andrés and Providencia island archipelago (Colombian territory) may be visible below. As the flight approaches Colombia, the northern Andes begin to appear — the Cordillera Occidental rises from the coastal lowlands, and the Cauca Valley becomes visible before the final descent into the Aburrá Valley.