Sit on the Left side of the plane for the best views on flights from Boston to Columbus. Left side wins both ends of the flight. During the cruise phase heading west-southwest, the left side also tracks closer to the southern edge of the Berkshires in Massachusetts and the Catskill foothills in New York, offering slightly more terrain interest than the right side's flatter view toward Long Island Sound and Pennsylvania.

During takeoff from General Edward Lawrence Logan International (BOS), sit on the Left side for the best views. Logan's most common westbound departures use Runway 22L/22R, heading southwest over Boston Harbor and the city. The left side gives you a direct view back over downtown Boston, the Charles River, and the harbor islands as you climb out. Right side faces toward the open Atlantic. Notable sights include: Downtown Boston skyline, Boston Harbor and its islands, Charles River and Cambridge, Fenway Park area.

When landing at Port Columbus International (CMH), sit on the Left side for the best views. CMH approaches from the east typically use Runway 28L/28R heading west, putting the left side over the city of Columbus and the Scioto River as you descend. The right side faces south toward suburban sprawl with fewer distinctive features. Notable sights include: Columbus downtown skyline, Scioto River, Ohio State University campus, Hoover Reservoir to the northeast.

The flight from General Edward Lawrence Logan International (BOS) to Port Columbus International (CMH) takes Approximately 1 hour 45 minutes to 2 hours.

The flight tracks west-southwest over the Berkshire Hills of western Massachusetts, then crosses the Hudson River valley in New York state, passes over the rolling Catskill foothills and the Pocono Plateau of northeastern Pennsylvania, then descends across the flat agricultural plains of central Ohio. The Susquehanna River valley is visible in Pennsylvania, and the broad Ohio River valley marks the transition into Ohio terrain.