Sit on the Right side of the plane for the best views on flights from Denver to Tucson. While the left side has a strong takeoff show with the Front Range, the right side wins overall. During cruise the flight tracks southwest over New Mexico, and the right side faces northwest capturing the San Juan Mountains of Colorado receding behind, then the Jemez Mountains and Rio Grande valley in New Mexico, and finally the Santa Catalinas on arrival. The right side delivers more sustained mountain scenery across the full flight.

During takeoff from Denver International (DEN), sit on the Left side for the best views. DEN typically departs south on runway 17L/17R or uses east/west runways. Departing southbound or turning southwest, the left (east-facing) side initially sees downtown Denver and the plains, but the right side gets the Rockies. However, on the common westbound departure turn toward Tucson, the left side captures the Front Range including Pikes Peak and the Denver metro spread across the plains below. Notable sights include: Front Range of the Rockies (Longs Peak to Pikes Peak), Denver downtown skyline, Chatfield Reservoir, the distinctive white tent roof of DEN terminal receding below.

When landing at Tucson International (TUS), sit on the Right side for the best views. TUS typically lands on runway 11L/11R (heading southeast) or runway 29 (heading northwest). On the common approach from the north/northeast, the right side faces west and southwest, giving views of the Santa Catalina Mountains directly north of Tucson and the Rincon Mountains to the east of the city. The right side also captures the Tucson basin and Saguaro National Park terrain on final. Notable sights include: Santa Catalina Mountains (Mount Lemmon at 9,157 ft), Rincon Mountains, Tucson city grid in the basin, Saguaro National Park desert terrain.

The flight from Denver International (DEN) to Tucson International (TUS) takes Approximately 1 hour 45 minutes to 2 hours.

The flight crosses the Sangre de Cristo Mountains and San Luis Valley in southern Colorado, then tracks over the Rio Grande corridor and high desert plateau of central New Mexico near Albuquerque, passing the Sandia Mountains to the east. The route then crosses the Mogollon Rim and the high desert of southeastern Arizona before descending into the Tucson basin.