Sit on the Right side of the plane for the best views on flights from Medellin to San Andres Island. Takeoff views from the right are significantly more dramatic due to the Cordillera Central's steep eastern face. While landing favors the left, the 45-minute flight duration means takeoff scenery dominates the experience. The climb-out offers the most distinctive geography on this route.

During takeoff from Olaya Herrera (EOH), sit on the Right side for the best views. Olaya Herrera typically departs runway 01 (northbound) or 19 (southbound). Right-side seats offer views of the Aburrá Valley's eastern ridge and the Cordillera Central rising sharply to the east, which dominates the climb-out profile. Left seats see the western valley wall and urban sprawl, less dramatic. Notable sights include: Cordillera Central (eastern ridge, 8,000-10,000 ft peaks), Aburrá Valley floor with Medellín's northern districts, Río Medellín winding through the valley, Arví Peak (2,560 m) to the northeast.

When landing at Gustavo Rojas Pinilla (ADZ), sit on the Left side for the best views. San Andres Island is approached from the southwest (typical runway 01 landing). Left-side seats provide unobstructed views of the Caribbean Sea, the island's distinctive crescent shape, and the surrounding shallow turquoise waters and coral formations. Right seats face the island's interior and Colombian mainland to the west, less visually rewarding. Notable sights include: Caribbean Sea (turquoise shallow waters), San Andres Island's crescent coastline with white sand beaches, Providencia Island (smaller, visible 50 km to the north on clear days), coral reef systems visible as darker patches in shallow water.

The flight from Olaya Herrera (EOH) to Gustavo Rojas Pinilla (ADZ) takes Approximately 45 minutes.

The flight path crosses northwest over the Caribbean coast near the Magdalena River delta, then over open Caribbean waters. At cruise altitude (around 20,000 feet), the Serranía de San Blas mountains are visible to the west (Panamanian territory, roughly 100 km away). The flight remains over water for most of the journey, with no major landmarks visible in the middle section except the distant Panamanian coast on the western horizon.