Sit on the Left side of the plane for the best views on flights from New York to Rio Negro. Left side wins at both ends of the flight. During the cruise over the Caribbean, the left side also offers occasional views of Cuba, Hispaniola, and the Colombian coast as the route tracks south-southwest, making it the stronger choice for the full journey.

During takeoff from John F Kennedy International (JFK), sit on the Left side for the best views. JFK primarily departs eastward over Jamaica Bay on runways 22L/22R or northward on 31L/31R. Left side gives you the best view of Lower Manhattan's skyline, the Verrazano-Narrows Bridge, and the Hudson River as the aircraft banks south toward its Caribbean heading. The right side faces the Atlantic Ocean and Long Island suburbs. Notable sights include: Lower Manhattan skyline, Verrazano-Narrows Bridge, Upper New York Bay, Jamaica Bay wetlands.

When landing at Jose Maria Cordova (MDE), sit on the Left side for the best views. Jose Maria Cordova airport sits in the Andes at 6,955 feet elevation, and aircraft typically approach from the east or northeast, descending over the Cauca Valley. The left side faces south toward Medellin's urban bowl and the surrounding Andes ridgelines, giving a dramatic view of the city nestled between steep green mountain slopes. The right side looks north over less populated Andean terrain. Notable sights include: Medellin urban valley, Andes cordillera ridgelines, Cauca River valley, Rio Negro plateau.

The flight from John F Kennedy International (JFK) to Jose Maria Cordova (MDE) takes Approximately 5 hours 30 minutes to 6 hours.

The flight tracks south-southwest over the Atlantic, crossing the Bahamas archipelago, then Cuba's elongated landmass, followed by the Caribbean Sea. The route passes near or over Hispaniola (Haiti and Dominican Republic) and Jamaica before crossing the Colombian coast near Cartagena and then climbing over the Andes foothills toward Medellin.