Sit on the Left side of the plane for the best views on flights from Minneapolis to Buffalo. While takeoff favors the right (Minneapolis views), the landing view of Lake Ontario and the Niagara River is more dramatic and geographically distinctive. The left side captures the most visually striking feature of this route.

During takeoff from Minneapolis St Paul International (MSP), sit on the Right side for the best views. Right-side seats capture the Mississippi River valley and downtown Minneapolis skyline during the initial climb. MSP typically departs runways 30L/30R or 12L/12R; eastbound departures on 30L/30R provide the best river and city views to the right. Notable sights include: Mississippi River (flowing south through Minneapolis), downtown Minneapolis skyline, Minnesota River confluence, Chain of Lakes district.

When landing at Buffalo Niagara International (BUF), sit on the Left side for the best views. Left-side seats offer views of Lake Ontario and the Niagara River during descent into Buffalo. Typical landing runways are 24L/24R or 6L/6R; westbound approaches on 24L/24R position Lake Ontario prominently on the left side during the final descent. Notable sights include: Lake Ontario (massive freshwater body), Niagara River (narrow strait between lakes), Niagara Falls (visible as mist/spray in good conditions), Canadian shoreline.

The flight from Minneapolis St Paul International (MSP) to Buffalo Niagara International (BUF) takes Approximately 2 hours 15 minutes.

The flight path crosses central New York State, passing over the Finger Lakes region (visible as elongated north-south water bodies), the Mohawk River valley, and the transition from Appalachian foothills to the Great Lakes plain. Lake Erie's southern shore becomes visible in the final 30 minutes of flight, with the Niagara River and Lake Ontario appearing in the last 15 minutes of descent.