Sit on the Left side of the plane for the best views on flights from New Orleans to Boston. The left side delivers the dramatic Mississippi River crescent and Lake Pontchartrain at departure, then tracks the Appalachian ridgelines through Virginia and Maryland in the mid-flight, and still catches glimpses of Boston Harbor on approach. The right side has a strong landing view but is largely over open Atlantic water during cruise, making left the better seat for the full journey.

During takeoff from Louis Armstrong New Orleans International (MSY), sit on the Left side for the best views. MSY's primary departure runway 20 sends aircraft southeast over the Mississippi River and Lake Pontchartrain. The left side captures the sweeping bend of the Mississippi, the French Quarter grid, and the full expanse of Lake Pontchartrain as the aircraft climbs and turns northeast. The right side faces mostly suburban sprawl toward Kenner. Notable sights include: Mississippi River crescent bend through downtown New Orleans, Lake Pontchartrain (631 sq mi open water), Lake Borgne to the east, New Orleans CBD skyline.

When landing at General Edward Lawrence Logan International (BOS), sit on the Right side for the best views. Logan Airport sits on a peninsula in Boston Harbor, and aircraft typically land on runway 04R/22L or 09/27 depending on wind. Approaches from the southwest on runway 04R bring the aircraft over the harbor from the south, putting Boston Harbor, the downtown skyline, and Cape Cod Bay on the right side. The left side faces inland toward suburban Boston and Route 128 corridor. Notable sights include: Boston Harbor and its islands, Boston downtown skyline (Prudential Tower, Hancock Tower), Cape Cod peninsula visible to the southeast, Quincy Bay.

The flight from Louis Armstrong New Orleans International (MSY) to General Edward Lawrence Logan International (BOS) takes Approximately 3 hours 15 minutes to 3 hours 45 minutes.

The flight tracks northeast over Mississippi and Alabama, crossing the Tennessee River valley, then over the Appalachian Mountains through Virginia and West Virginia where the parallel ridges of the Blue Ridge and Allegheny ranges are clearly visible from altitude. Over Maryland and Delaware the Chesapeake Bay is a major landmark — its long narrow form unmistakable from 35,000 feet. The flight then crosses the New Jersey Pine Barrens and the Hudson River corridor before the Connecticut coastline and Long Island Sound come into view on descent toward Boston.