Sit on the Right side of the plane for the best views on flights from New Orleans to St. Louis. Right-side seats provide superior views on both departure and arrival. The northbound flight path follows the Mississippi River valley, and right seats offer consistent views of the river's meanders, the transition from Louisiana's delta terrain to Missouri's river bluffs, and both cities' key landmarks.

During takeoff from Louis Armstrong New Orleans International (MSY), sit on the Right side for the best views. MSY typically departs on Runway 10L/10R (eastbound) or 28L/28R (westbound). Eastbound departures favor right seats for views of Lake Pontchartrain's northern shore and the Mississippi River delta. Westbound departures on right seats show the city grid and industrial areas along the river. Notable sights include: Lake Pontchartrain (north), Mississippi River meanders (south/southwest), New Orleans city grid and CBD (west), industrial canal and port facilities (immediate vicinity).

When landing at Lambert St Louis International (STL), sit on the Right side for the best views. Approach to STL typically uses Runways 30L/30R (eastbound) or 12L/12R (westbound). Right-seat passengers on eastbound approaches see the Mississippi River valley, the city of St. Louis on the western bank, and the Gateway Arch as the descent progresses. Westbound approaches also favor right seats for river and city views. Notable sights include: Mississippi River (dominant feature, flowing north-south), St. Louis city skyline and Gateway Arch (west bank), Illinois bluffs and terrain (east bank), Lambert Airport runways and surrounding suburban development.

The flight from Louis Armstrong New Orleans International (MSY) to Lambert St Louis International (STL) takes Approximately 1 hour 15 minutes.

The flight path follows the Mississippi River northward through central Louisiana and into Arkansas. Notable features include the river's major meanders near Vicksburg, Mississippi (approximately 45 minutes into flight), the transition from flat delta terrain to slightly elevated bluff country, and the Arkansas-Missouri border region where the river valley becomes more pronounced. The river remains the dominant geographic reference throughout the flight, visible from cruising altitude as a continuous brown ribbon winding through increasingly forested terrain.