Sit on the Right side of the plane for the best views on flights from Prague to Madrid. Right-side seats offer superior scenery on both legs: Prague's river and urban landscape during takeoff, and continuous views of the Bohemian and Bavarian landscapes, the Danube valley, and the Alpine foothills during cruise. Left seats favor only the landing approach.

During takeoff from Ruzyne (PRG), sit on the Right side for the best views. Right-side seats offer views of the Vltava River valley and Prague's urban sprawl spreading south and southwest from Ruzyně. The city's distinctive layout along the river is clearly visible during the initial climb-out. Notable sights include: Vltava River (winding through Prague below), Prague city center and Old Town districts, Petřín Hill with its observation tower, Šumava foothills to the southwest.

When landing at Barajas (MAD), sit on the Left side for the best views. Left-side seats provide excellent views of the Sierra de Guadarrama mountain range during the descent approach to Madrid from the north. The mountains form a dramatic natural barrier north of the city and are prominently visible on final approach. Notable sights include: Sierra de Guadarrama (snow-capped peaks visible on clear days), Meseta Central plateau, Madrid's urban sprawl and Retiro Park, Manzanares River valley.

The flight from Ruzyne (PRG) to Barajas (MAD) takes Approximately 2 hours 15 minutes.

The flight path crosses the Bohemian Forest (Šumava) on the Czech-German border, then follows the Danube River valley through Bavaria and Austria. Notable midpoint landmarks include the Danube's course near Passau (where the Inn and Ilz rivers converge), the Bavarian Alps appearing as a distant ridge on the left (west) side around cruise altitude, and the transition from Central European forests to the drier Spanish plateau as the aircraft approaches the Iberian Peninsula. The Pyrenees are typically too far south to be visible on this routing, but the Spanish meseta's characteristic flat, arid terrain becomes increasingly dominant in the final hour of flight.