Sit on the Left side of the plane for the best views on flights from Knoxville to Santa Ana. While takeoff offers mountain scenery on the right, the landing approach on the left provides more varied and dramatic geography—mountains, basin, ocean, and islands—making it the superior choice for the full journey.

During takeoff from Mc Ghee Tyson (TYS), sit on the Right side for the best views. Right-side seats offer views of the Great Smoky Mountains as the aircraft climbs westward out of Knoxville. The ridgelines and valleys are particularly striking during the initial climb phase before the aircraft reaches cruising altitude. Notable sights include: Great Smoky Mountains National Park (south and southeast), Tennessee River valley (north), Knoxville urban area (beneath and behind during climb).

When landing at John Wayne Arpt Orange Co (SNA), sit on the Left side for the best views. Left-side seats provide excellent views during the descent approach to Santa Ana. You'll see the San Gabriel Mountains to the north and the sprawling Los Angeles basin with its urban grid, plus the Pacific coastline and offshore islands as you descend toward Orange County. Notable sights include: San Gabriel Mountains (north), Los Angeles basin urban sprawl (center and north), Pacific Ocean and Catalina Island (west and southwest), Santa Ana River valley (south).

The flight from Mc Ghee Tyson (TYS) to John Wayne Arpt Orange Co (SNA) takes 4h 15m.

The flight path crosses the Mississippi River valley (near Memphis area), then continues over the Texas Panhandle and New Mexico high plains. Notable features include the Ozark plateau region (eastern portion), the Canadian River valley, and the transition into the Colorado Plateau terrain. The Rio Grande valley becomes visible in the final approach phase toward Southern California.