Sit on the Left side of the plane for the best views on flights from Amsterdam to Panama City. While the right side wins at takeoff for Amsterdam views, the left side dominates the majority of the flight. Heading southwest across the Atlantic and then south along the Caribbean, the left side faces east and south, offering views of the Iberian Peninsula coast, the Canary Islands region, West African coastline in the distance, and then the Caribbean islands as you approach Central America. The Panama City arrival view on the left is also the more dramatic of the two endpoints.

During takeoff from Schiphol (AMS), sit on the Right side for the best views. Schiphol typically departs southwest on runway 18R/24 or northwest on 36C/36R. A right-side seat gives you views over Amsterdam city center, the IJ river, and the distinctive polder landscape of Noord-Holland. You can clearly see the canal ring pattern of central Amsterdam and the IJmeer to the east. Notable sights include: Amsterdam canal ring, IJmeer/IJsselmeer, Haarlem and its surrounding polders, North Sea coastline.

When landing at Tocumen International (PTY), sit on the Left side for the best views. Tocumen typically lands on runway 03L/03R or 21, approaching from the south or north over the Bay of Panama. A left-side seat gives you the best view of Panama City's skyline, the Pacific entrance to the Panama Canal, and the Bridge of the Americas. The Miraflores Locks may be visible on clear days during the approach. Notable sights include: Panama City skyline, Bridge of the Americas, Pacific entrance to the Panama Canal, Bay of Panama.

The flight from Schiphol (AMS) to Tocumen International (PTY) takes Approximately 11 to 12 hours.

The route tracks southwest over the English Channel, then across the Bay of Biscay and the Iberian Peninsula or just off its Atlantic coast, passing near the Canary Islands. It then crosses the Atlantic on a great circle arc, passing north of the Cape Verde Islands. The route enters the Caribbean basin, crossing over or near the Lesser Antilles, then tracks southwest over the Caribbean Sea passing north of Colombia before descending into Panama. The San Blas archipelago off Panama's Caribbean coast may be visible on descent.