Sit on the Left side of the plane for the best views on flights from Buffalo to Chicago. The left side delivers the best views at both ends of this flight — Lake Erie and the Niagara corridor on departure, and the Chicago lakefront and skyline on approach. The right side offers little of comparable interest on either end.

During takeoff from Buffalo Niagara International (BUF), sit on the Left side for the best views. Buffalo Niagara typically departs runway 23 heading southwest, which puts the left side facing southeast toward Lake Erie and the Niagara River corridor. You get a clear view of the lake shoreline and can often spot the Niagara Falls mist plume to the north-northeast as the aircraft banks. Notable sights include: Lake Erie shoreline, Niagara River corridor, Niagara Falls mist plume (to the north), downtown Buffalo waterfront.

When landing at Chicago Ohare International (ORD), sit on the Left side for the best views. Flights from Buffalo typically approach O'Hare from the east on runways 10L/10R or similar easterly headings, placing the left side facing north toward Lake Michigan's southern shoreline and the Chicago lakefront. The left side gives you the city grid, the lakefront parks, and the downtown skyline as you descend. Notable sights include: Chicago downtown skyline (Loop), Lake Michigan southern shoreline, Chicago lakefront parks, O'Hare suburban sprawl.

The flight from Buffalo Niagara International (BUF) to Chicago Ohare International (ORD) takes Approximately 1 hour to 1 hour 15 minutes.

The flight tracks roughly west-southwest across northern Indiana, passing over the flat agricultural plains of the Lake Erie lowlands and then Indiana farmland. Lake Michigan's southern tip may be briefly visible to the right (north) side as you approach Chicago. The terrain is uniformly flat with few dramatic features mid-flight, though the patchwork of Indiana and Ohio farmland is visible below.