Sit on the Left side of the plane for the best views on flights from Newark to Sao Paulo. The left side delivers the iconic Manhattan and New York Harbor departure view, which is one of the most spectacular urban takeoffs in aviation. During the flight the left side also faces east toward the Atlantic for most of the southbound routing, and on approach into GRU the left side looks north over less dramatic terrain. The takeoff experience on the left is the decisive factor.

During takeoff from Newark Liberty International (EWR), sit on the Left side for the best views. EWR typically departs south on runway 22L/22R or northeast on 4L/4R. On a southbound departure toward GRU, a left-side seat gives you Manhattan's skyline and the Hudson River as you climb out, then the Verrazano-Narrows Bridge and Upper New York Bay. On a northeast departure, left side still captures the Manhattan skyline across the water to the northwest. Notable sights include: Manhattan skyline, Hudson River, Verrazano-Narrows Bridge, Upper New York Bay.

When landing at Guarulhos (GRU), sit on the Right side for the best views. GRU typically lands on runways 09R/27L or 09L/27R oriented east-west. On a westward approach from the Atlantic, right-side seats look south toward the Serra do Mar coastal escarpment and the sprawling São Paulo metropolitan grid. The approach over the city gives a clear view of the dense urban fabric of Guarulhos and northern São Paulo spreading to the horizon. Notable sights include: Serra do Mar escarpment, São Paulo metropolitan grid, Tietê River valley, Guarulhos urban area.

The flight from Newark Liberty International (EWR) to Guarulhos (GRU) takes Approximately 9 to 10 hours.

The route tracks southeast over the Atlantic Ocean, passing east of the Caribbean island chain. The Amazon River delta and the vast Amazon basin rainforest canopy are visible from altitude over northern Brazil — the river system appears as a braided network of brown waterways cutting through unbroken dark green forest. The cerrado transition zone of central Brazil appears as a patchwork of agricultural clearing and savanna as the flight descends toward São Paulo.