Sit on the Right side of the plane for the best views on flights from Frankfurt to Nairobi. The right side wins overall due to the extraordinary Nairobi National Park arrival view, which is one of the most unusual urban-wildlife juxtapositions visible from any approach in the world. During the cruise, the right side also tracks closer to the Nile Valley over Sudan and the Ethiopian highlands on the eastern horizon, though both sides offer similar views over the Sahara and East African plateau.

During takeoff from Frankfurt Main (FRA), sit on the Left side for the best views. Frankfurt typically departs southward on runway 25C/25R or uses 07L/07R depending on wind. On a southbound departure toward Africa, the aircraft turns left (southeast), putting the left side over the Rhine-Main plain with Frankfurt city center, the Main River, and the Taunus hills visible. The right side faces open farmland toward Darmstadt. Notable sights include: Frankfurt city skyline and banking district, the Main River curving through the city, Taunus hills to the northwest, Sachsenhausen district south of the Main.

When landing at Nairobi Wilson (WIL), sit on the Right side for the best views. Nairobi Wilson Airport sits just south of central Nairobi and typically uses runway 07 (eastward approach) or 14 (southeast). On approach from the north, the right side faces east toward the Nairobi National Park and the Athi Plains, while the left faces the city. However, the right side on final approach gives a clear view of Nairobi National Park's open savanna with the city skyline as a backdrop — a genuinely striking combination unique to this airport. Notable sights include: Nairobi National Park savanna and wildlife plains, Nairobi city skyline to the north, Ngong Hills to the southwest, Athi Plains stretching east.

The flight from Frankfurt Main (FRA) to Nairobi Wilson (WIL) takes Approximately 8 to 9 hours.

The flight tracks southeast over the Alps (briefly), then across the Mediterranean near Sicily or Malta, over Libya and the Sahara Desert with its vast sand seas and ergs, crossing into Sudan near Khartoum where the Blue and White Nile confluence is visible, then over the Ethiopian highlands with deeply eroded plateau terrain, before descending across the flat Kenyan savanna toward Nairobi.