Sit on the Left side of the plane for the best views on flights from Indianapolis to Charlotte. The left side wins overall. The Indianapolis departure view of the downtown skyline and Lucas Oil Stadium is the most visually rewarding moment of the flight. During cruise the left side also tracks slightly closer to the Kentucky and Tennessee border terrain. The landing view from the right is good but the uptown Charlotte skyline is relatively compact and the approach is over flat suburban terrain.

During takeoff from Indianapolis International (IND), sit on the Left side for the best views. IND primarily uses runways 5L/5R and 23L/23R. Departing southeast toward CLT on runway 5, the left side looks northeast over downtown Indianapolis, giving a clear view of the city grid, the White River corridor, and Lucas Oil Stadium. The right side faces open farmland with little of interest. Notable sights include: Downtown Indianapolis skyline, Lucas Oil Stadium, White River corridor, Indianapolis Motor Speedway (visible to the northwest during initial climb).

When landing at Charlotte Douglas International (CLT), sit on the Right side for the best views. CLT typically uses runways 18C/36C and 18L/36R oriented north-south, with arrivals from the north common for flights from Indianapolis. On a northerly approach, the right side faces east toward uptown Charlotte, giving a clear view of the city skyline and the broader Piedmont landscape. The left side looks west over less distinctive suburban sprawl. Notable sights include: Uptown Charlotte skyline, Bank of America Stadium, Lake Norman (visible to the north during descent), Catawba River.

The flight from Indianapolis International (IND) to Charlotte Douglas International (CLT) takes Approximately 1 hour 30 minutes.

The flight tracks southeast across southern Indiana farmland, crosses the Ohio River near Louisville or slightly east of it, then passes over central Kentucky's rolling Bluegrass region and horse farm country. It crosses into Tennessee briefly or clips the Tennessee-North Carolina border area, then descends over the Carolina Piedmont — gently rolling terrain with mixed forest and suburban development — into Charlotte. No major mountain ranges are crossed, though the distant Blue Ridge may be faintly visible on the eastern horizon during descent.