Sit on the Right side of the plane for the best views on flights from Las Vegas to Portland. The right side wins overall because the Las Vegas departure offers the most dramatic and immediate scenery — the Strip plus the Spring Mountains — and during the cruise northward through Oregon, the right side picks up the central Oregon Cascades including the Three Sisters and Crater Lake region on clear days. The left side landing view of Mount Hood is excellent but brief.

During takeoff from Mc Carran International (LAS), sit on the Right side for the best views. McCarran typically departs northbound on runway 26L/R or 19L/R. A right-side seat gives you the Las Vegas Strip running north-south below, then the Spring Mountains and Red Rock Canyon escarpment to the west as you climb out. Left side gets the suburban sprawl of Henderson. Notable sights include: Las Vegas Strip (casino corridor), Red Rock Canyon escarpment, Spring Mountains (Charleston Peak at 11,918 ft), Lake Mead to the east visible briefly on right turn north.

When landing at Portland International (PDX), sit on the Left side for the best views. Portland International sits on the south bank of the Columbia River and typically lands on runways 28L/R (westbound approach) or 10L/R (eastbound). On the common westbound approach from the east, left-side seats get Mount Hood directly ahead and to the south, plus the Columbia River Gorge. Right side faces north toward Washington state flatlands. Notable sights include: Mount Hood (11,249 ft volcanic cone), Columbia River Gorge, Mount St. Helens (visible to the north on clear days), Portland city center west of the airport.

The flight from Mc Carran International (LAS) to Portland International (PDX) takes Approximately 2 hours 15 minutes.

The flight tracks north-northwest over the Great Basin of Nevada, crossing the high desert plateau country around Winnemucca and the Humboldt River valley. Entering Oregon, the route passes over the Basin and Range terrain of southeastern Oregon, then crosses the High Lava Plains and the Deschutes River canyon system. The central Oregon Cascades — including the Three Sisters volcanic group, Broken Top, and Mount Jefferson — are visible to the west on the right side during cruise. The Columbia Plateau's broad flat basalt terrain dominates the final descent corridor into Portland.