Sit on the Right side of the plane for the best views on flights from La Paz to Santa Cruz. Right-side seats dominate this route: the departure offers the Cordillera Real and Altiplano escarpment (the most dramatic geography), and the landing still provides good views of the Rio Grande and forest transition. Left wins only on landing approach.

During takeoff from El Alto International (LPB), sit on the Right side for the best views. El Alto typically departs eastbound (Runway 01/19 operations favor eastbound traffic). Right-side seats capture the dramatic escarpment of the Altiplano dropping away toward the Amazon basin, plus the snow-capped peaks of the Cordillera Real to the southeast. Notable sights include: Cordillera Real (Illimani and Huayna Potosí peaks), the Altiplano plateau edge, Lake Titicaca (visible on clear days to the northwest, but secondary), the steep descent into the Yungas cloud forest zone.

When landing at Viru Viru International (VVI), sit on the Left side for the best views. Viru Viru typically uses Runway 03/21 with eastbound approaches common. Left-side seats offer views of the Rio Grande and the transition from Chiquitano forest to the developed Santa Cruz valley. The approach path crosses the agricultural plains and urban sprawl of Santa Cruz city. Notable sights include: Rio Grande (meandering through lowland forest), Santa Cruz city grid and urban development, Chiquitano dry forest (transitional vegetation zone), the flat agricultural plains of the eastern lowlands.

The flight from El Alto International (LPB) to Viru Viru International (VVI) takes Approximately 1 hour 15 minutes.

The flight path descends from 13,615 feet at El Alto through the Yungas cloud-forest zone (steep valleys with dense vegetation), crosses the transition from high Andes to lowland Amazon basin, passes over the Beni region's forested plains, and approaches the Chiquitano forest and agricultural plains surrounding Santa Cruz. The Rio Grande and its tributaries become visible in the descent phase. Clear-day flights may show the full escarpment profile and the dramatic altitude loss over roughly 200 miles of horizontal distance.