Sit on the Left side of the plane for the best views on flights from Chicago to Spokane. While takeoff favors the right for Lake Michigan views, the landing approach on the left provides more sustained scenic interest over the final 45 minutes, with the Spokane River valley and surrounding plateau terrain offering distinctive visual landmarks. The left side captures the destination geography more dramatically.

During takeoff from Chicago Midway International (MDW), sit on the Right side for the best views. Right side offers views of Lake Michigan immediately after departure, with the Chicago skyline receding behind. The lake dominates the eastern horizon during the initial climb-out heading northwest toward Spokane. Notable sights include: Lake Michigan, Chicago downtown skyline, Des Plaines River valley, suburban Chicago grid.

When landing at Spokane International (GEG), sit on the Left side for the best views. Left side provides excellent views of the Spokane River valley and the city's location within the Columbia Plateau during descent. The river and surrounding terrain are prominent on approach from the west. Notable sights include: Spokane River, Spokane city grid, Palouse Hills to the south, Columbia Plateau terrain.

The flight from Chicago Midway International (MDW) to Spokane International (GEG) takes Approximately 3 hours 45 minutes.

The flight path crosses central Wisconsin (forests and lakes), then transitions into Minnesota and Iowa farmland (regular grid patterns, Mississippi River valley near the Minnesota-Iowa border), followed by the Great Plains of South Dakota and Nebraska (flat to gently rolling terrain with sparse vegetation), and finally enters the Columbia Plateau of eastern Washington with increasingly visible elevation changes and the Cascade Range foothills appearing on the western horizon during descent.