Sit on the Left side of the plane for the best views on flights from Mexico City to Medellin. While takeoff favors the right for Mexico City's eastern terrain, the landing approach into Medellín's confined Aburrá Valley strongly favors left-side seating for the dramatic Cordillera Occidental views and the final descent corridor. The landing experience is more visually distinctive and geographically significant than the takeoff.

During takeoff from Licenciado Benito Juarez International (MEX), sit on the Right side for the best views. MEX typically departs eastbound (Runways 05L/05R) or westbound (Runways 23L/23R). For southbound routing toward Medellín, eastbound departure is standard. Right-side seats capture the Sierra de Guadalupe and the eastern sprawl of Mexico City's urban grid as you climb out, with clear views of the valley terrain that defines the climb corridor. Notable sights include: Sierra de Guadalupe (north of city center), Lake Texcoco remnants and wetland areas (east), Mexico City's eastern suburbs and industrial zones, Popocatépetl volcano (distant southeast, weather permitting).

When landing at Olaya Herrera (EOH), sit on the Left side for the best views. Olaya Herrera (EOH) sits on Medellín's northwestern edge at 4,905 feet elevation. Approach typically comes from the north or northeast, descending into the Aburrá Valley. Left-side seats provide direct views of the Cordillera Occidental (Western Range) that frames the valley's western wall, the city's northern neighborhoods, and the final descent path into the narrow valley. Notable sights include: Cordillera Occidental ridge (western valley wall), Medellín's northern districts and Río Medellín (flowing north-south through city), Aburrá Valley floor with surrounding peaks, Arví mountain (eastern valley rim, visible across the city).

The flight from Licenciado Benito Juarez International (MEX) to Olaya Herrera (EOH) takes Approximately 2 hours 15 minutes to 2 hours 45 minutes.

The flight path crosses south through central Mexico (Guerrero state), passing east of Acapulco and the Sierra Madre del Sur. You'll traverse the Isthmus of Tehuantepec region, then enter Central America crossing Guatemala and into Colombia. The Pacific coast remains visible to the west for much of the southern Mexico portion. As you approach Colombia, the Andes begin to dominate the landscape, with multiple parallel cordilleras becoming visible. The descent into Medellín brings you into the narrow Aburrá Valley surrounded by the three branches of the Colombian Andes.