Sit on the Left side of the plane for the best views on flights from Santa Cruz to Sao Paulo. While takeoff offers some geological interest on the right, the landing approach on the left provides superior views of major geographic features—the Serra da Mantiqueira and river valleys—that frame São Paulo's setting. The left side captures the transition from mountains to metropolitan area, which is more visually and geographically rewarding for the majority of the flight's final phase.

During takeoff from Viru Viru International (VVI), sit on the Right side for the best views. VVI typically departs on runway 09 (westbound) or 27 (eastbound). Right-side seats offer views of the Serranía del Itenez escarpment and the transition from Santa Cruz's urban sprawl into the Bolivian lowlands. The terrain rises noticeably to the south and southeast, creating visual relief during climb-out. Notable sights include: Serranía del Itenez (distant ridge to the south), Rio Grande valley floor, Santa Cruz city grid, transition zone between cultivated land and rainforest.

When landing at Guarulhos (GRU), sit on the Left side for the best views. GRU typically lands on runway 09L/09R (eastbound approach) or 27L/27R (westbound). Left-side seats during descent offer clear views of the Paraíba do Sul River valley and the Serra da Mantiqueira mountain range to the north. The approach path crosses the Tietê River and its floodplain, providing geographic context for the São Paulo metropolitan area's sprawling layout. Notable sights include: Serra da Mantiqueira (northern horizon), Tietê River and floodplain, Paraíba do Sul River valley, São Paulo metropolitan urban grid.

The flight from Viru Viru International (VVI) to Guarulhos (GRU) takes Approximately 3 hours 15 minutes.

The flight crosses the Mato Grosso do Sul plateau and enters the São Paulo state highlands. Notable features include the transition from Cerrado savanna to Atlantic Forest remnants, the Paraná River basin to the south (not directly visible but defines the regional hydrology), and the gradual rise in elevation as the aircraft approaches the Serra da Mantiqueira system. The landscape shifts from flat lowlands to rolling highlands with increasing vegetation density.