Sit on the Right side of the plane for the best views on flights from Detroit to Fort Myers. Right-side seats dominate both segments—Detroit River and Windsor on departure, then the entire Gulf Coast estuary system on arrival. This provides the most geographically distinctive views for the full journey.

During takeoff from Detroit Metro Wayne Co (DTW), sit on the Right side for the best views. DTW typically departs runways 3L/3R or 22L/22R. Right-side seats offer views of the Detroit River and Windsor, Ontario across the water, plus the sprawling suburban development south toward Ann Arbor. Left side shows inland lakes and residential areas but less distinctive geography. Notable sights include: Detroit River (immediate southeast), Windsor Ontario skyline, Lake St. Clair (northeast in distance), suburban sprawl extending toward Ann Arbor.

When landing at Southwest Florida International (RSW), sit on the Right side for the best views. RSW uses runways 6/24 primarily. Right-side seats during approach show the Caloosahatchee River estuary, Sanibel Island, and the Gulf of Mexico coastline with its barrier islands. Left side shows inland swamps and development but less dramatic water features. Notable sights include: Caloosahatchee River estuary, Sanibel Island and barrier islands, Gulf of Mexico, Estero Bay.

The flight from Detroit Metro Wayne Co (DTW) to Southwest Florida International (RSW) takes Approximately 2 hours 45 minutes.

The flight path crosses Ohio and Kentucky, passing east of Cincinnati and Louisville. The Ohio River is occasionally visible in breaks between cloud cover. As the aircraft descends into Florida airspace, the landscape transitions from deciduous forest to pine flatlands and wetlands. The Gulf Coast becomes visible roughly 50 miles north of RSW, with the distinctive barrier island chain running parallel to the mainland.