Sit on the Left side of the plane for the best views on flights from Dubai to Karachi. The left side wins overall because the Dubai departure offers the most visually interesting moment of the flight — the Creek, the coastline, and the city grid all at once during climb-out. The cruise portion over the Arabian Sea and Sindh desert is largely featureless on both sides, and the Karachi arrival views are comparable. The Dubai departure on the left is the highlight of this short route.

During takeoff from Dubai International (DXB), sit on the Left side for the best views. Dubai International's primary departure runway 30L/30R sends aircraft heading northwest before turning east toward Karachi. A left-side seat captures the Dubai Creek, Deira district, and the coastline of the Arabian Gulf as the aircraft banks right over the city. You get a clear look down at the dense urban grid of old Dubai before it gives way to desert. Notable sights include: Dubai Creek and Deira waterfront, Palm Deira reclamation area, Sharjah urban sprawl to the north, Arabian Gulf coastline.

When landing at Jinnah International (KHI), sit on the Right side for the best views. Karachi's runway 25L/25R has aircraft approaching from the east over the Arabian Sea, meaning a right-side seat looks south over the open sea while the left side faces the city. However, runway configuration often has arrivals on 07R coming in from the west, which puts the city of Karachi, Manora Island, and Karachi Harbour directly on the right side during final approach. The right seat gives the better urban and coastal panorama on the more common eastward landing direction. Notable sights include: Karachi Harbour and Manora Island, Clifton Beach and Defence Housing Authority coastline, Karachi city centre grid, Indus delta mudflats to the northeast.

The flight from Dubai International (DXB) to Jinnah International (KHI) takes Approximately 2 hours 15 minutes.

The flight tracks roughly east-northeast across the Arabian Sea, passing south of the Makran Coast of Pakistan — a rugged, sparsely populated desert coastline with occasional river mouths and fishing settlements visible as thin brown lines meeting the sea. The Indus River delta's mudflat fingers may be visible on the left side during descent into Karachi, appearing as a dark brown branching pattern where the river meets the Arabian Sea.