Sit on the Right side of the plane for the best views on flights from Newark to Guatemala City. While the left side wins at takeoff with Manhattan views, those last only a few minutes. The right side delivers the dramatic Guatemalan volcanic approach which is one of the most visually striking airport approaches in the Americas. Over the 4.5-hour flight, the right side also gets better views of the Yucatan Peninsula coastline and Gulf of Mexico as the route curves southwest.

During takeoff from Newark Liberty International (EWR), sit on the Left side for the best views. EWR's primary departure runway 22L sends aircraft southwest over New Jersey, then curving south. The left side gets Manhattan's skyline directly across the Hudson River during initial climb, including the full sweep of Lower Manhattan and Midtown. Right side faces inland New Jersey with far less visual interest. Notable sights include: Manhattan skyline (Lower Manhattan to Midtown), Hudson River, Statue of Liberty in New York Harbor, Verrazano-Narrows Bridge.

When landing at La Aurora (GUA), sit on the Right side for the best views. La Aurora airport sits in Guatemala City's southern urban area, and aircraft typically approach from the north or northeast on runway 02, meaning a southward landing. The right side faces west toward the volcanic chain — Volcán de Agua, Volcán de Fuego, and Acatenango are dramatically visible on approach. The left side looks east over the city and valley with less distinctive scenery. Notable sights include: Volcán de Agua, Volcán de Fuego, Volcán Acatenango, Guatemala City urban valley.

The flight from Newark Liberty International (EWR) to La Aurora (GUA) takes Approximately 4 hours 30 minutes to 5 hours.

The route tracks southwest over the Mid-Atlantic states, then across Cuba or the western Caribbean, over the Yucatan Peninsula (right side gets Gulf of Mexico views, left gets Caribbean), across the Gulf of Honduras, and into the Guatemalan highlands. The Sierra de los Cuchumatanes mountain range in northwestern Guatemala is visible on descent. Cuba's elongated island shape is often visible from cruising altitude as the route passes near its western end.