Sit on the Left side of the plane for the best views on flights from Firenze to Frankfurt. Left side wins both ends of the flight. During the cruise over the Alps and southern Germany, the left side also faces generally west-southwest, giving views toward the Black Forest and Rhine valley as the route tracks north. Right side gets the eastern Alps and Po Plain on departure, but the left side's city and river views at both airports are more dramatic.

During takeoff from Peretola (FLR), sit on the Left side for the best views. Florence's runway 05/23 means departures heading northeast give the left side a direct view over the historic city center and the Arno valley. You'll see the Duomo, Ponte Vecchio area, and the hills of Fiesole before climbing into the Apennines. Notable sights include: Florence historic center (Duomo visible), Arno River valley, Fiesole hills, northern Apennine ridgelines.

When landing at Frankfurt Main (FRA), sit on the Left side for the best views. Frankfurt typically uses runways 25L/25R or 07L/07R. On the common westward approach (runway 25), aircraft track in from the east over the Rhine-Main region, and the left side faces south toward Frankfurt's skyline and the Main River. The Taunus hills are also visible to the left on final approach. Notable sights include: Frankfurt city skyline (Bankenviertel towers), Main River, Taunus hills to the northwest, Rhine-Main plain.

The flight from Peretola (FLR) to Frankfurt Main (FRA) takes Approximately 1 hour 45 minutes to 2 hours.

The route crosses the northern Apennines shortly after departure, then transits the Po Plain of northern Italy. It crosses the Alps — likely over or near the Brenner Pass corridor or slightly west — giving views of high Alpine terrain including glaciated peaks. Over southern Bavaria the route passes near Munich before tracking northwest across the Swabian Alb and into the Rhine-Main basin approaching Frankfurt.