Sit on the Right side of the plane for the best views on flights from Frankfurt to Firenze. While left is better at takeoff from Frankfurt, the right side wins on the approach into Florence with the iconic city center, Duomo, and Arno River directly in view at low altitude — that arrival view is the highlight of this route. En route, the right side also picks up better views of the Po Plain and northern Apennines during descent.

During takeoff from Frankfurt Main (FRA), sit on the Left side for the best views. Frankfurt typically departs on runway 25L/25C heading west-southwest, then turns south. The left side picks up the Main River valley, Frankfurt's city center skyline, and the Taunus hills to the north as the aircraft banks south. Right side faces open farmland toward Darmstadt. Notable sights include: Frankfurt city skyline (Bankenviertel towers), Main River bend, Taunus hills ridge, Sachsenhausen district rooftops.

When landing at Peretola (FLR), sit on the Right side for the best views. Florence's Peretola airport uses runway 05 for arrivals from the northwest, meaning the aircraft approaches from the northwest tracking southeast. The right side faces south toward the Arno valley and the historic city center of Florence, with the Duomo and Ponte Vecchio area clearly visible on final approach at low altitude. The left side looks toward the Apennine foothills. Notable sights include: Florence city center with Duomo di Firenze, Arno River, Ponte Vecchio area, Fiesole hills to the northeast.

The flight from Frankfurt Main (FRA) to Peretola (FLR) takes Approximately 1 hour 40 minutes.

The flight tracks southeast over Bavaria and the Alps foothills, crossing the Brenner Pass corridor or skirting east of it depending on routing, then descending over the broad Po Plain of northern Italy. The northern Apennines are crossed on the final descent into Florence, with the Arno valley opening up below.