Sit on the Left side of the plane for the best views on flights from Guayaquil to Sao Paulo. While takeoff favors the right for estuary views, the landing approach on the left provides superior views of São Paulo's dramatic geography—the Tietê River valley and mountain ranges. The landing experience outweighs the takeoff advantage.

During takeoff from Simon Bolivar International (GYE), sit on the Right side for the best views. GYE typically departs eastbound (Runway 09). Right-side seats offer views of the Andes foothills rising inland and the Guayas River estuary spreading west toward the Pacific. Left seats face the ocean with less dramatic terrain. Notable sights include: Guayas River estuary (braided waterways below), Andes western slopes (distant ridgeline), Pacific coastline (western horizon), Salinas Peninsula (southwestern edge).

When landing at Guarulhos (GRU), sit on the Left side for the best views. GRU typically lands westbound (Runway 27L or 27R). Left-side seats during descent offer views of the São Paulo metropolitan sprawl, the Tietê River valley, and the Serra da Mantiqueira mountains to the south. Right seats face industrial suburbs with less geographic interest. Notable sights include: Tietê River (winding through urban landscape), Serra da Mantiqueira (southern mountain range), São Paulo metropolitan grid (urban sprawl), Cantareira Mountains (northern ridgeline).

The flight from Simon Bolivar International (GYE) to Guarulhos (GRU) takes Approximately 3 hours 15 minutes.

The flight path crosses the Amazon Basin and transitions into the Brazilian Shield. Notable features include the Negro River (tributary system, visible as dark water channels around 1.5 hours into flight), the transition from equatorial rainforest to cerrado savanna (color change from dense green to lighter tan-green), and the approach to the Brazilian Plateau's eastern edge. The Mantiqueira and Serra do Mar mountain ranges become visible approximately 30 minutes before landing as a distant ridgeline on the southern horizon.