Sit on the Left side of the plane for the best views on flights from Panama City to Denver. Left side wins both ends of the flight. During the cruise over Central America and Mexico you also get better views of the Gulf of Mexico coastline and the Sierra Madre Occidental as the route tracks northwest, making left the clear choice for the full journey.

During takeoff from Tocumen International (PTY), sit on the Left side for the best views. Tocumen typically departs northwest on runway 03L/03R or northeast, but the dominant departure toward the US routes the aircraft northwest over Panama Bay. Left side gives you Panama Bay and Panama City's skyline including the Cinta Costera waterfront, while right side faces inland jungle. Notable sights include: Panama Bay, Panama City skyline and Cinta Costera, Bridge of the Americas over the Panama Canal, Miraflores Locks area.

When landing at Denver International (DEN), sit on the Left side for the best views. Denver International sits on the plains east of the Rockies and typically lands from the east or southeast on runways oriented north-south. Left side on approach from the south gives a clear broadside view of the entire Front Range including Pikes Peak to the south and Longs Peak to the north, with Denver's downtown grid visible below. Notable sights include: Rocky Mountain Front Range, Pikes Peak (14,115 ft), Longs Peak (14,259 ft), Denver downtown skyline.

The flight from Tocumen International (PTY) to Denver International (DEN) takes Approximately 6 to 6.5 hours.

The route tracks northwest over Costa Rica and Nicaragua, then across the Gulf of Tehuantepec, over southern Mexico and the Sierra Madre Occidental mountain ranges, across the Chihuahuan Desert of northern Mexico, over the US border near El Paso or New Mexico, then across the high desert plateau of New Mexico and Colorado before descending to Denver. The Sierra Madre Occidental ridgelines are visible from altitude as a broad corrugated mountain spine running parallel to the Mexican Pacific coast.