Sit on the Left side of the plane for the best views on flights from Seattle to Cleveland. Left side wins at both ends of the flight. At departure you get Mount Rainier and the Seattle waterfront; at arrival you get the Cleveland skyline and Lake Erie shoreline. During cruise the left side also faces generally south, giving slightly better views of the northern Rockies and Great Plains terrain as the route tracks east-southeast.

During takeoff from Seattle Tacoma International (SEA), sit on the Left side for the best views. SEA typically departs north on runway 16R/34L or south on 16L/34R. Northbound departures turning east give the left side a clear view of Mount Rainier to the southeast and the Seattle skyline to the north. Even on southbound departures, the left side tracks over Puget Sound and the Olympic Peninsula is visible to the west while Rainier dominates the left horizon. Notable sights include: Mount Rainier (14,411 ft, unmistakable snow cone to the southeast), Seattle downtown skyline and Elliott Bay, Lake Washington (large freshwater lake east of Seattle), Puget Sound waterway.

When landing at Cleveland Hopkins International (CLE), sit on the Left side for the best views. CLE typically lands on runway 06/24 or 10/28. Approaches from the west over Lake Erie put the left side facing south over the Cleveland downtown skyline, the Cuyahoga River valley, and the lakefront. The right side faces north over open Lake Erie water with little to see. Notable sights include: Cleveland downtown skyline (Key Tower, Rocket Mortgage FieldHouse visible), Lake Erie shoreline, Cuyahoga River winding through the Flats district, Burke Lakefront Airport on the lakefront.

The flight from Seattle Tacoma International (SEA) to Cleveland Hopkins International (CLE) takes Approximately 4 hours 15 minutes to 4 hours 45 minutes.

The route crosses the northern Rocky Mountains over Montana and Idaho, where the Bitterroot Range and Clark Fork River valley are visible. Over North Dakota and Minnesota the terrain flattens into the Great Plains and then the glacially-scoured Upper Midwest lake country. The Great Lakes region begins as you cross into Wisconsin and Michigan, with Lake Michigan visible to the south before crossing into Ohio.