Sit on the Right side of the plane for the best views on flights from Charlotte to Anchorage. While left offers the Appalachian climb-out, right dominates the flight overall. The right side captures the dramatic Chugach Mountains and Turnagain Arm during descent—the most visually striking segment of this 4.5-hour flight. The approach to Anchorage is far more geographically distinctive than the departure from Charlotte.

During takeoff from Charlotte Douglas International (CLT), sit on the Left side for the best views. Left side offers views of the Appalachian Mountains as the aircraft climbs northwest out of Charlotte. The ridgelines and valleys of the Blue Ridge become visible within 15–20 minutes of departure, providing clear topographic contrast against the Piedmont lowlands below. Notable sights include: Blue Ridge Mountains, Catawba River valley, Charlotte urban grid, Piedmont plateau terrain.

When landing at Ted Stevens Anchorage International (ANC), sit on the Right side for the best views. Right side provides views of the Chugach Mountains and Turnagain Arm during descent into Anchorage. The dramatic coastal geography—the arm's tidal flats, the snow-capped peaks, and Cook Inlet—are best seen from the right as the aircraft approaches from the southeast. Notable sights include: Chugach Mountains, Turnagain Arm, Cook Inlet, Anchorage coastal plain.

The flight from Charlotte Douglas International (CLT) to Ted Stevens Anchorage International (ANC) takes 4h 45m.

The flight path crosses the Great Plains (Kansas, Nebraska, Colorado), the Rocky Mountains (Colorado Front Range and Wyoming ranges), the intermountain basins of Montana and Idaho, and the Cascade Range in Washington before turning north over British Columbia and the Alaska panhandle. Notable visible features include the Colorado Front Range near Denver, the Absaroka and Beartooth ranges in Montana, and the volcanic peaks of the Cascades (Mount Rainier, Mount Hood) in the Pacific Northwest. The flight then crosses into Alaska, passing over the Alaska Range and the Talkeetna Mountains before descending toward Anchorage.