Sit on the Left side of the plane for the best views on flights from Iquitos to Cartagena. While takeoff favors the right for Amazon River views, the landing approach to Cartagena is visually superior—the Caribbean coastline, colonial city, and island archipelago provide more dramatic and varied scenery. Left seats capture the most distinctive features of the destination.

During takeoff from Coronel Fap Francisco Secada Vignetta (IQT), sit on the Right side for the best views. Iquitos sits on a meander of the Amazon River. Right-side seats offer immediate views of the river's oxbow lakes and the dense rainforest canopy spreading eastward. The river's distinctive brown water and surrounding wetlands are most visible on the right during northwesterly departure. Notable sights include: Amazon River meanders and oxbow lakes, Nanay River confluence, dense lowland rainforest canopy, Iquitos city grid along riverbank.

When landing at Rafael Nunez (CTG), sit on the Left side for the best views. Approaching Cartagena from the southeast, left-side seats provide excellent views of the Caribbean coastline, Cartagena's historic walled city on its peninsula, and the nearby Rosario Islands. The city's distinctive layout and turquoise coastal waters are most prominent on the left during descent. Notable sights include: Caribbean Sea and coastline, Cartagena walled old city and peninsula, Rosario Islands archipelago, Boca Grande strait.

The flight from Coronel Fap Francisco Secada Vignetta (IQT) to Rafael Nunez (CTG) takes Approximately 3 hours 15 minutes.

The flight path crosses the northwestern Amazon Basin, transitioning from dense rainforest in Peru to more open terrain as it approaches Colombia. The Putumayo River and its tributaries may be visible as brown water channels cutting through the canopy in the midpoint. As the aircraft climbs to cruise altitude (typically 28,000-32,000 feet), individual rivers become harder to distinguish, but the transition from flat Amazonian lowlands to slightly more undulating terrain near the Colombian border is noticeable. The Serranía de la Macarena (a low mountain range) lies south of the direct flight path but may be visible as a distant ridge on the horizon during cruise. No major cities are encountered along the route until approach to Cartagena.