Sit on the Right side of the plane for the best views on flights from Phoenix to Louisville. While the takeoff offers desert scenery, the landing approach provides more dramatic and distinctive geography with the Ohio River's prominent meanders and Louisville's riverfront setting. The river views are more visually striking than the gradual desert transition on departure.

During takeoff from Phoenix Sky Harbor International (PHX), sit on the Left side for the best views. Left side offers immediate views of the Phoenix metropolitan area and the surrounding desert terrain. As the aircraft climbs northeast out of PHX, the left wing reveals the Salt River valley and the transition from urban sprawl to the Sonoran Desert. Notable sights include: Phoenix downtown skyline, Salt River valley floor, McDowell Mountains to the northeast, Sonoran Desert scrubland extending eastward.

When landing at Louisville Muhammad Ali International Airport (SDF), sit on the Right side for the best views. Right side provides excellent views during the descent into Louisville. The aircraft approaches from the west-southwest, and the right wing reveals the Ohio River and the distinctive geography of the Louisville area, including the river's major bend and the city's position along its banks. Notable sights include: Ohio River with its characteristic meanders, Louisville downtown and riverfront district, Shawnee Park area, surrounding Kentucky bluegrass landscape.

The flight from Phoenix Sky Harbor International (PHX) to Louisville Muhammad Ali International Airport (SDF) takes 3h 15m.

The flight path crosses the Mississippi River valley near Memphis, Tennessee; the Ozark Plateau in Missouri and Arkansas; and the Cumberland River drainage system in Kentucky. The most notable midpoint feature is the Mississippi River itself, visible as a wide, meandering waterway with distinctive oxbow lakes, typically seen around 1.5 hours into the flight when cruising at altitude over western Tennessee.